Careers at NIBRT
The multi-award winning National Institute for Bioprocessing Research and Training (NIBRT) is a global centre of excellence for training and research in bioprocessing. NIBRT offers a variety of careers in the areas of research, training and contract research.
Current Career Opportunities
VACANCY SUMMARY
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POSITION AVAILABLE |
Post Doc Researcher (Formulation and Stability) |
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LOCATION |
Dublin, Ireland |
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DEPARTMENT |
Formulation and Stability |
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HIRING MANAGER |
Elizabeth Topp |
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CONTRACT TYPE |
3 Years Fixed Term |
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SALARY & BENEFITS |
Competitive salary and excellent suite of benefits. Benefits include: pension, private health insurance, income protection scheme, 25 days annual leave plus up to 3 additional company days off, generous training and career development supports, flexible working hours and work from home set up supported |
|
APPLICATION DATE |
Open for applications |
|
INTERVIEW DATES |
As soon as available (position to be filled as soon as possible) |
ORGANISATION OVERVIEW
The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin that provides training and research solutions to the global biopharmaceutical manufacturing sector. NIBRT arose from an innovative collaboration between University College Dublin, Trinity College Dublin, Dublin City University and the Institute of Technology, Sligo, with core funding by the Government of Ireland through Ireland’s inward investment agency, IDA Ireland. NIBRT’s 6,500 M² facility has 80 employees currently and houses fully operational pilot plants for biologics manufacturing training to industry and education as well as multiple research laboratories focussed on biopharmaceuticals manufacturing research.
ROLE SUMMARY
mRNA vaccines are a promising approach to preventing infectious diseases and treating some forms of cancer, but they are remarkably unstable, requiring ultracold temperatures for shipping and storage. The broad goal of this research program is to develop innovative stabilization strategies for mRNA vaccines, grounded in a thorough understanding of mRNA degradation mechanisms and enabled by novel manufacturing methods.
This project will explore the mechanisms of mRNA degradation under formulation relevant conditions, evaluating the effectiveness of chemical modifications in improving stability. In currently accepted solution-state mechanisms for mRNA degradation, the reaction occurs by intramolecular nucleophilic attack of the 2’OH of the ribose on the phosphorous atom of the phosphodiester bond. This suggests that chemical modifications that hinder this reaction may be stabilizing. However, current mechanisms have been established using di- and tri-nucleoside model compounds at elevated temperature; the mechanisms of degradation for full-length mRNA under formulation relevant conditions are not known.
This project will begin to address these deficiencies. The successful applicant for this postdoctoral position will develop analytical methods, perform stability studies, produce mRNA by IVT, perform post-transcriptional modifications, and conduct in vitro evaluation. The individual also will provide in-laboratory support for the Ph.D. students, prepare initial drafts of manuscripts and reports, give regular oral presentations of research progress, present research findings at meetings and conferences, and contribute to the overall management and upkeep of the laboratory. The project has considerable potential for generating intellectual property (IP) related to mRNA stabilization.
This position is targeted to an experienced postdoctoral researcher, holding an earned Ph.D. and having completed one or more years of postdoctoral research (SFI Level 2B). The position is ideally suited to candidates with doctoral degrees in chemistry, chemical engineering, pharmaceutical chemistry, or closely related fields, and with demonstrated expertise in the chemical analysis of biomolecules, chemical synthesis and/or nanoparticle production and characterization, as well as strong communication and interpersonal skills. Additional preferred qualifications include previous hands-on experience with mass spectrometry, capillary electrophoresis, ATR-FTIR, and/or LNP production and characterization, and/or statistical analysis and experimental design. An understanding of and previous experience with nucleotide synthesis would be highly advantageous. The project is supported by a grant from Science Foundation Ireland.
KEY RESPONSIBILITIES
- Conducting research in mRNA stability and chemical modification under the leadership of the Principal Investigator, including (but not limited to) preparation and characterization of mRNA and chemically modified mRNA, development of analytical methods, preparation and characterization of mRNA loaded lipid nanoparticles (LNP), and assessment of the translation of mRNA and chemically modified mRNA to protein using in vitro methods;
- Maintaining detailed and orderly records of the work performed, making them available to the Principal Investigator upon request;
- With the PI and NIBRT Research Office, ensuring timely reporting to the research sponsor (Science Foundation Ireland);
- Disseminating the outcomes of this research in poster and/or podium presentations at regional, national, and international meetings and conferences;
- Preparing manuscripts for publication in top-tier journals;
- Participating fully in the wider research and scholarly activities of the group within the remit and restrictions of the appointed position;
- Carrying out any other duties within the scope, spirit and purpose of the job as requested by the Principal Investigator;
- Complying with all NIBRT policies and regulations, including those in relation to Research Ethics and Health and Safety.
REQUIREMENTS
- An earned PhD in chemistry, chemical engineering, pharmaceutical chemistry, or a relevant related discipline from an approved degree awarding institution (essential).
- At least one year of relevant postdoctoral research experience.
- Commitment to research excellence (essential).
- Effective oral and written communication skills: report writing, knowledge transfer and communication skills with the ability to present complex information effectively to a range of audiences (essential).
- Self-motivated and able to work collaboratively and as part of a team to an agreed work plan (essential).
DESIRABLE CRITERIA
- Experience in the synthesis of chemically modified nucleosides and/or oligonucleotides.
- Experience in physicochemical analysis of nucleosides and/or oligonucleotides using methods such as NMR and mass spectrometry.
- Experience working in multidisciplinary research teams.
APPLICATION PROCESS
To apply for this position please forward your CV and cover letter to careers@nibrt.ie
Please include your name and the position which you are applying for in the subject line. Please note that the successful candidate may be required to supply parchments of degrees/qualifications/work permits. Informal enquiries can be made in confidence by contacting our Project Manager, Therese Keohane at careers@nibrt.ie.
VACANCY SUMMARY
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POSITION AVAILABLE |
PhD Student |
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LOCATION |
Dublin, Ireland |
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DEPARTMENT |
Formulation & Stability |
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HIRING MANAGER |
Elizabeth Topp |
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CONTRACT TYPE |
Fixed term |
|
SALARY & BENEFITS |
Competitive salary and excellent suite of benefits. Benefits include: pension, private health insurance, income protection scheme, 25 days annual leave plus up to 3 additional company days off, generous training and career development supports, flexible working hours and work from home set up supported |
|
APPLICATION DATE |
Open for applications |
|
INTERVIEW DATES |
As soon as available (position to be filled as soon as possible) |
ORGANISATION OVERVIEW
The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin that provides training and research solutions to the global biopharmaceutical manufacturing sector. NIBRT arose from an innovative collaboration between University College Dublin, Trinity College Dublin, Dublin City University and the Institute of Technology, Sligo, with core funding by the Government of Ireland through Ireland’s inward investment agency, IDA Ireland. NIBRT’s 6,500 M² facility has 90+ employees currently and houses fully operational pilot plants for biologics manufacturing training to industry and education as well as multiple research laboratories focussed on biopharmaceuticals manufacturing research.
ROLE PURPOSE
Recombinant proteins and other biologics are the fastest growing sector of the pharmaceutical industry, but the chemical and physical instability of these complex molecules can make formulation difficult. One of the most common types of instability for recombinant protein drugs is aggregation, the covalent or non-covalent association of two or more protein molecules. Protein aggregates typically have altered potency relative to their monomeric counterparts (sub- or super-potent) and an increased potential for adverse immune responses in patients. These adverse immune responses can range from the production of anti-drug antibodies (ADA), which inactivate the drug, to life-threatening anaphylaxis. As a result, the biopharmaceutical industry and regulatory agencies are committed to eliminate aggregates during manufacturing, shipping, and shelf-storage to ensure that patients receive a safe and efficacious product.
This project will explore covalent modification as a route to inhibiting protein aggregation. Two types of modifications will be considered: (i) irreversible modification and (ii) reversible modification. The latter is an example of a pro-drug strategy, in which the active pharmaceutical ingredient (API) is chemically modified in a way that is readily reversed on administration in the body. The work will build on the group’s recent successes with phosphate ester prodrugs of fibrillation-prone peptide drugs, extending the approach to larger proteins (see e.g., Fibrillation of human calcitonin and its analogs: Effects of phosphorylation and disulfide reduction. H. Renawala, K. Chandrababu, E. M. Topp. Biophys. J., 120/1: 86-100, 2021). The PhD student will enroll as in the Department of Chemical and Bioprocess Engineering at University College Dublin. He/she will report to the PI/CSO (Elizabeth Topp) and will be assisted by postdoctoral scientists and others in the lab. The project supported by an ITN Doctoral Network through the University of Groningen; secondments to other universities in the network are possible.
This position is ideally suited to a researcher with a background in chemistry, biochemistry, chemical engineering, pharmaceutical chemistry, or related field. An understanding of basic biochemistry, particularly protein chemistry, would be highly advantageous. An honours degree (NFQ Level 8) is required.
KEY RESPONSIBILITIES
- Conducting doctoral level research under the leadership of the Principal Investigator and/or senior postdoc.
- Maintaining detailed and orderly records of the work performed, making them available to the Principal Investigator and/or senior postdoc upon request.
- Disseminating the outcomes of this research in poster and/or podium presentations at regional, national, and international meetings and conferences.
- With collaborators and co-authors, generating manuscripts for publication in top-tier journals.
- Fulfilling all requirements of the ITN and the host department.
- Participating fully in the wider research and scholarly activities of the group within the remit and restrictions of the appointed position and complying with all policies and regulations, including those in relation to Research Ethics and Health and Safety.
REQUIREMENTS
- A BSc in chemistry, biochemistry, chemical engineering, pharmaceutical chemistry, or a relevant related discipline from an approved degree awarding institution.
- Commitment to research excellence.
- Effective oral and written communication skills: report writing, knowledge transfer and communication skills with the ability to present complex information effectively to a range of audiences.
- Self-motivated and able to work collaboratively and as part of a team to an agreed work plan.
DESIRABLE CRITERIA
- Prior experience in an industrial or academic research laboratory.
- Experience in the biopharmaceutical industry and/or as an analytical chemist, e.g. quality control laboratories, industry, research.
- Experience working in multidisciplinary research teams.
TERMS
This is an EU funded (Greener RPP) position which is open to candidates who have not resided, worked, or studied in Ireland for more than 12 months of the last 36 months. It is a requirement that you have not previously completed a PhD.
APPLICATION PROCESS
To apply for this position please forward your CV and cover letter to careers@nibrt.ie
Please include your name and the position which you are applying for in the subject line. Please note that the successful candidate may be required to supply parchments of degrees/qualifications/work permits. Informal enquiries can be made in confidence by contacting our Project Manager, Therese Keohane at careers@nibrt.ie
VACANCY SUMMARY
Position Available: Research Fellow
Department: Bioinformatics and Data Analysis Group
Hiring Manager: Dr Colin Clarke, PI Bioinformatics
Contract Type: Fixed Term 2 Years
Location: NIBRT Facility, Dublin, Ireland
Benefits: Benefits include: pension, private health insurance, income protection scheme, 25 days annual leave plus up to 3 additional company days off, generous training and career development supports, flexible working hours and work from home set up supported
Application Date: Open for applications
Interview Dates: October-November 2022
About Us
The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin that provides training and research solutions to the global biopharmaceutical manufacturing sector. NIBRT’s 6,500 M² facility has 90+ employees currently and houses fully operational pilot plants for biologics manufacturing training to industry and education as well as multiple research laboratories focussed on biopharmaceuticals manufacturing research.
PROJECT SUMMARY
Cell therapy is the transfer of intact, live cells into a patient to treat or cure a disease. Cell-based immunotherapy and in particular, modified-cell immunotherapy such as CAR-T, has been delivering spectacular results for cancer patients and is an entirely novel approach to treating cancer. Immune cells are removed from the patient’s blood and engineered to identify and attack the cancer cells when they are reintroduced into the patient.
NIBRT PI Dr Colin Clarke, is hiring a Bioinformatics Research Scientist funded for 2 years through under the Irish Government’s Disruptive Technology Innovation Fund (DTIF). The successful candidate will be joining a team focussed on understanding and optimising the CAR-T cell manufacturing process. The Bioinformatics Research fellow will play a key role in this project by analysing single cell RNA-seq, single nuclei ATAC-seq and single cell protein measurements from CAR-T cells. There will also be opportunities to contribute to the analysis of other exciting projects within NIBRT.
EXAMPLE PUBLICATIONS FROM THE CLARKE LABORATORY
- Tzani et al. Understanding the transcriptional response to ER stress in Chinese hamster ovary cells using multiplexed single cell RNA-seq. bioRxiv (2022).
- Castro-Rivadeneyra et. al. Found in translation: Microproteins are a new class of potential host cell impurity in mAb drug products. bioRxiv (2022).
- Charitidis et al. Monitoring CAR T cell generation with a CD8-targeted lentiviral vector by single-cell transcriptomics. Molecular Therapy (2021).
- Tzani et al. Tracing production instability in a clonally derived CHO cell line using single‐cell transcriptomics. Biotechnology and Bioengineering (2021).
DUTIES & RESPONSIBILITIES
- Conducting a specific programme of research under the leadership of the Principal Investigator
- Maintaining detailed and orderly records of the work performed, making them available to the Principal Investigator upon request
- Disseminating the outcomes of this research at project meetings and through written reports
- Preparing and presenting progress reports and research findings to colleagues for review purposes
- Engaging in appropriate training and professional development opportunities as determined by the Principal Investigator
- Carrying out any other duties within the scope, spirit and purpose of the job as requested by the Principal Investigator
ESSENTIAL & DESIRABLE CRITERIA
- A PhD in Bioinformatics or related discipline is essential.
- Experience working with Linux.
- Proficient in programming languages such as R and/or Python.
- Experience in the analysis next generation sequencing data is essential.
- Experience with a range of different data types is desirable (e.g., RNA-seq or ATAC-seq).
- Experience with single cell RNA-seq or single nuclei ATAC-seq data is highly desirable.
- Familiar with version control e.g., Git
- Excellent scientific writing skills
- Effective oral and written communication skills: report writing, knowledge transfer and communication skills with the ability to present complex information effectively to a range of audiences
How To Apply
To apply for this position please forward your CV, cover letter and the names and contact details of two referees in a combined PDF document to careers@nibrt.ie. Please include your name and the position for which you are applying for in the subject line. Please note that the successful candidate may be required to supply parchments of degrees/qualifications/work permits. Informal enquiries should be directed to Dr Colin Clarke (colin.clarke@nibrt.ie)
VACANCY SUMMARY
Position Available: Research Fellow
Department: Cell Engineering
Hiring Manager: Niall Barron, PI
Contract Type: Fixed Term 2 Years
Location: GSK Belgium & NIBRT
Benefits: Benefits include: pension, private health insurance, income protection scheme, 25 days annual leave plus up to 3 additional company days off, generous training and career development supports, flexible working hours and work from home set up supported
Application Date: Open for applications
Interview Dates: As soon as available (position to be filled as soon as possible)
About Us
The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin that provides training and research solutions to the global biopharmaceutical manufacturing sector. NIBRT’s 6,500 M² facility has 90+ employees currently and houses fully operational pilot plants for biologics manufacturing training to industry and education as well as multiple research laboratories focussed on biopharmaceuticals manufacturing research.
GSK is one of the world’s largest vaccines companies, delivering vaccines that help protect people at all stages of life. Its R&D focuses on developing vaccines against infectious diseases that combine high medical need and strong market potential.
GSK’s Vaccines business has a portfolio of more than 20 vaccines to help protect people from a range of diseases throughout their lives and the company supplies these vaccines to people living in over 160 countries.
Innovation is the beating heart of GSK’s business. Without it, there will be no new vaccines for the many diseases that still threaten individuals, families and communities around the world.
GSK’s Vaccines scientists work in three global R&D centres, in Belgium, Italy and the US. The company has long track record of collaborating with governments, healthcare providers, regulators, academic institutions, non-governmental organisations, vaccine producers and other key partners to tackle public health challenges around the world.
Project Summary
Chinese hamster ovary (CHO) cells are one of the most widely-used cell lines for recombinant protein production. A combination of in silico protein design, optimised expression vectors, stringent selection systems and optimised bioprocess conditions has meant high product yields with human-like glycosylation patterns are now routinely achieved. However, in some instances certain recombinant proteins are clipped or degraded during the production process, reducing yield and compromising the safety and the product potency, leading to an increase of manufacturing challenges. This project will focus on identifying the mechanism(s) causing the degradation of a small panel of recombinant vaccine antigens during expression in CHO cells and establishing strategies to prevent it. In particular it will employ a CRISPR knockout library to target genetic causes of this phenomenon. Building on the fundamental understanding of mechanisms leading to protein degradation we aim at generating a panel of novel parental CHO cell lines suitable for the production of clipping-prone proteins. This is an exciting collaboration between NIBRT and GSK and represents a unique opportunity for an ambitious postdoctoral scientist to spend time working on a highly applied scientifically challenging project. The successful candidate will have an opportunity to work in both NIBRT and GSK, splitting their time between the two locations.
Key Responsibilities:
- Conducting a specific programme of research under the leadership of the Principal Investigators
- Maintaining detailed and orderly records of the work performed, making them available to the Principal Investigator upon request
- Disseminating the outcomes of this research at project meetings and through written reports
- Preparing and presenting progress reports and research findings to colleagues for review purposes
- Engaging in appropriate training and professional development opportunities as determined by the Principal Investigators
- Carrying out any other duties within the scope, spirit and purpose of the job as requested by the Principal Investigators including routine lab management and maintenance duties
Requirements:
- A PhD in molecular/cell biology or related discipline essential. Postdoctoral experience highly desirable.
- Extent and breadth of experience in the following techniques in an academic or industrial environment will dictate level of appointment and salary;
- Experience in mammalian cell culture
- Experience with nucleic acid manipulation and analysis – cloning, qPCR, etc
- Some experience with gene/protein delivery methods – transfection, electroporation, viral transduction etc.
- Experience with targeted genetic engineering highly desirable, including CRISPR-based approaches and guide RNA design
- Strong interest in applied research
- Excellent writing and documentation skills
- Effective oral and written communication skills: report writing, knowledge transfer and communication skills with the ability to present complex information effectively to a range of audiences
What we will offer you:
At NIBRT we believe that our role is to make a positive difference in everything that we do. Each of us has an important contribution to make and we’re committed to doing so in a way that drives equality in how we work, where we work and what we do.
We offer a competitive salary and an excellent benefits package, including health insurance, pension, and life assurance. Work/life balance is key to happy and motivated colleagues, and we offer 25 days annual leave plus up to 3 additional company days off.
We are committed to supporting and developing our team members through educational assistance. There’s also our professional EAP that’s there 24/7 if you ever need assistance or support.
NIBRT is committed to equal employment opportunities for all, we embrace difference and treat everyone with respect.
How To Apply
To apply for this position please forward your CV and cover letter to careers@nibrt.ie
Please include your name and the position which you are applying for in the subject line. Please note that the successful candidate may be required to supply parchments of degrees/qualifications/work permits. Informal enquiries can be made in confidence by contacting our Project Manager, Therese Keohane at careers@nibrt.ie
NIBRT is an Equal Opportunities Employer.
VACANCY SUMMARY
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POSITION AVAILABLE |
Research Communication and Outreach Officer |
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LOCATION |
Dublin, Ireland (Hybrid) |
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DEPARTMENT |
Research Office |
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HIRING MANAGER |
Jennifer Byrne, Associate Director of Research |
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CONTRACT TYPE |
Permanent |
|
SALARY & BENEFITS |
Competitive salary and excellent suite of benefits. Benefits include: pension, private health insurance, income protection scheme, 25 days annual leave plus up to 3 additional company days off, generous training and career development supports, flexible working hours and work from home set up supported |
|
APPLICATION DATE |
Open for applications |
|
INTERVIEW DATES |
As soon as available (position to be filled as soon as possible) |
ORGANISATION OVERVIEW
The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin that provides training and research solutions to the global biopharmaceutical manufacturing sector. NIBRT arose from an innovative collaboration between University College Dublin, Trinity College Dublin, Dublin City University and the Institute of Technology, Sligo, with core funding by the Government of Ireland through Ireland’s inward investment agency, IDA Ireland. NIBRT’s 6,500 M² facility has 90+ employees currently and houses fully operational pilot plants for biologics manufacturing training to industry and education as well as multiple research laboratories focussed on biopharmaceuticals manufacturing research.
ROLE PURPOSE
The National Institute for Bioprocessing Research and Training (NIBRT) is seeking candidates for the post of Research Communications and Outreach Officer. This role will be based within the NIBRT Research Office.
The NIBRT Research Office supports NIBRT researchers in applying for funding under national and international funding programmes as well as through direct funding from industry partners.
The NIBRT Research Office plays a key role in supporting NIBRT researchers in the management of their funded research activities. In order to support wider dissemination and promotion of the high-quality research ongoing in NIBRT, the Research Office has created a new role focused on Research Communication and Outreach.
We are seeking a scientifically literate, motivated, and effective communicator who will spearhead the development and delivery of the NIBRT Research Team’s communication activities. The successful candidate will be expected to have a good working knowledge of the scientific areas underpinning research in the manufacture of biopharmaceuticals and be willing to learn more about biopharmaceutical manufacturing research. The successful candidate will be instrumental in growing and developing the profile of the organisation and support the delivery of research output and information across a variety of communication channels. This will include the maintenance of websites, social media and other digital communications related to NIBRT research.
KEY RESPONSIBILITIES
- To regularly disseminate information relating to NIBRT research activities through a variety of channels, online or otherwise
- To contribute to and engage with members of the NIBRT Research Team including Principal Investigators (PIs), Post-Doctoral Researchers, postgraduate students, Research Assistants and members of the Research Office in the development of new outreach/communication opportunities, including taking a lead role in the development of creative materials and resources such as educational resources, information graphics and publications.
- Provide public engagement and outreach expertise, knowledge, and specialist input into research proposals developed by NIBRT PIs and researchers.
- To liaise with the NIBRT Marketing Manager to maintain and update resources on-line, including the NIBRT Research website, social media platforms and digital communications.
- To plan, develop and deliver an agreed annual programme of Communications and Outreach activities and events for the NIBRT Research team, with key partners and stakeholders as appropriate.
- To organise, co-ordinate and support the delivery of key research-focused engagement events such as conferences, seminars, workshops and training events.
- With other Research Office team members, assist with the management of the NIBRT research output log including the collation and production of relevant data required for reporting to stakeholders or for NIBRT publications (e.g. NIBRT’s Annual Report);
- To support NIBRT’s Research Office, Chief Scientific Officer and Chief Executive Officer in the provision of key communications metrics to assess the reach and impact of the organisation and its outreach activities.
- To support NIBRT with current outreach activities such as the NIBRT Transition Year programme
- To support NIBRT as an organisation in the development of submissions for awards or other measures of esteem.
- To develop and maintain key partnerships with external stakeholders such as research collaborators and partners, State agencies and sectoral stakeholders for the dissemination of information and to maximise publicity about the work of the NIBRT Research team.
- If appropriate, apply for funding to support specific outreach activities or collaborate with others on such applications (e.g. via the SFI Discover Programme)
- Any other duties as may be reasonably required from time to time in respect of this post.
ESSENTIAL CRITERIA
NIBRT is seeking a driven individual who is highly motivated, focused upon results and has a passion for discussing and disseminating research to fulfil this role.
To qualify, you must have:
- Research skills/education to Masters level in a subject relevant to the post.
- Minimum 2 years of experience of research communication activities, to include both of the areas of essential experience outlined below:
- At least 6 months experience of formulating, delivering, and evaluating public outreach, education or communication activities ideally relating to biomedical or bio/pharmaceutical science
- At least 6 months experience of managing and delivering public outreach and communication through the use of digital platforms including management of websites, social media platforms and digital communications. - Excellent interpersonal/communication skills and an ability to work effectively with research team members, management, and other stakeholders across all levels, both internally and externally.
- Ability to manage a varied and demanding schedule of priorities.
- Ability to work on own initiative and within tight deadlines.
- Ability to think creatively and independently.
- Ability to develop new skills as may be required by the role.
DESIRABLE CRITERIA
- A PhD Degree in a discipline closely related to the post
- Project management skills/qualification would be desirable.
REQUIRED SKILLS & COMPETENCIES
- Excellent written and verbal communication skills.
- Excellent practical skills in the delivery of Communications and Outreach activities.
- Strong organisation and time management skills.
- Sound academic and professional knowledge about Communications and Outreach involving areas of research encompassed by the NIBRT Research team (for example, analytical chemistry, biomedical research, proteomics, genomics, manufacturing).
- Accuracy and attention to detail essential.
- Strong interpersonal skills and ability to work well with others including a wide range of audiences that include specialist practitioners and general interest groups.
- Ability to prioritise workload.
- Flexibility and adaptability in the context of remote working arrangements.
APPLICATION PROCESS
To apply for this position please forward your CV and cover letter to careers@nibrt.ie
Please include your name and the position which you are applying for in the subject line. Please note that the successful candidate may be required to supply parchments of degrees/qualifications/work permits.
Informal enquiries can be made in confidence by contacting our Associate Director of Research, Jennifer Byrne at jennifer.byrne@nibrt.ie
VACANCY SUMMARY
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POSITION AVAILABLE |
E-Learning Content Developer |
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LOCATION |
Dublin, Ireland |
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DEPARTMENT |
Training Department |
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HIRING MANAGER |
John Milne, Director of Training |
|
CONTRACT TYPE |
Permanent |
|
SALARY & BENEFITS |
Competitive salary and excellent suite of benefits. Benefits include: pension, private health insurance, income protection scheme, 25 days annual leave plus up to 3 additional company days off, generous training and career development supports, flexible working hours and work from home set up supported |
|
APPLICATION DATE |
Open for applications |
|
INTERVIEW DATES |
As soon as available (position to be filled as soon as possible) |
ORGANISATION OVERVIEW
The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin that provides training and research solutions to the global biopharmaceutical manufacturing sector. NIBRT arose from an innovative collaboration between University College Dublin, Trinity College Dublin, Dublin City University and the Institute of Technology, Sligo, with core funding by the Government of Ireland through Ireland’s inward investment agency, IDA Ireland. NIBRT’s 6,500 M² facility has 90+ employees currently and houses fully operational pilot plants for biologics manufacturing training to industry and education as well as multiple research laboratories focussed on biopharmaceuticals manufacturing research.
ROLE PURPOSE
The NIBRT Online Academy (NOA) has grown significantly since its initial launch in January 2020. The platform delivers on demand learning on key aspects of biopharmaceutical manufacturing developed by leading industry experts. Users can access the modules online in their own time and study at their own pace. NOA provides a quality, efficient and cost-effective training solution from a recognised global leader in biopharmaceutical training. The interactive modules offer engaging multi-media content including video tutorials from subject matter experts, 3D models, animations and virtual simulations.
NIBRT wishes to appoint an E-Learning Content Developer to contribute to the continued successful implementation and future growth of NOA. The content developer will be responsible for the development and maintenance of key content for NOA, working directly with members of NIBRT’s Training team and associated commercial business units.
KEY RESPONSIBILITIES
Reporting to the Director of Training the key duties of the E-Learning Content Developer will include:
- Drive the ongoing development and success of the NIBRT Online Academy by leading the development of high quality online training solutions.
- Responsibility for creating and maintaining high quality learning content from NIBRT’s industry leading core curriculum in line with deadlines and approved budgets.
- Develop E-Learning training solutions to address key learning objectives of NIBRT’s target audience, integrating adult learning best practices and thought leadership into eLearning courses.
- Manage strict deadlines whilst ensuring a high-end user experience.
- Work with internal stakeholders to design evaluation methods and metrics to ensure learning outcomes have been achieved.
- Conduct independent research and generate ideas for improvement of educational materials.
- Liaise directly with NIBRT’s Training Team on the online development of training material including lectures and practical content in upstream, downstream, fill finish and support areas.
- Drive initiatives for the design and delivery of new and expanded methods of training (e.g. AR, VR, IR etc.) and work with NIBRT partners to ensure NIBRT fulfill its obligations to same.
- Liaise with current and prospective clients to understand their online training needs and assist NIBRT secure their business by supporting the development and delivery of solutions to these needs.
- Be fully informed of industry practices and changes to ensure NIBRT is fully up to date in relation to client needs and future industry changes and needs.
- Provide support to the NIBRT Training Team to develop their competence in online -Learning development.
- Represent the training department at company events (which may on occasion be during evenings or weekends).
- Monitor the NOA support inbox and on occasion, provide basic customer support/ trouble shooting for users on the NOA platform. Address changes and feedback to course deliverables in a timely manner.
- Comply with and maintain appropriate SOPs for the development and maintenance of content on the NOA platform Work with internal stakeholders to ensure training design fits with the overall vision for the area and business requirement.
- Any other reasonable duties as may be required from time to time by your manager.
REQUIREMENTS
- 3-5 years’ experience in learning design and content development with clear experience in generating effective instructional text, audio and video scripts that support key learning objectives and strategy is essential for this role.
- Detailed knowledge of leading online authoring and Learning Management Systems (Docebo® learning suite) required.
- Highly IT competent with detailed knowledge of digital content generation and management.
- Preferable to hold a degree in related scientific field (Life Science/Biopharmaceutical Processing/Engineering) with relevant biopharmaceutical industry experience an advantage.
- Excellent interpersonal skills both written and oral and ideally be an accomplished presenter.
- Possess required job knowledge to successfully fulfil or exceed the requirements of the post.
- The successful person will be a motivated self-starter, capable of working under their own initiative as part of a busy and dynamic training team.
ADDITIONAL IDEAL CRITERIA
- Practical knowledge of biopharmaceuticals, mammalian cell culture and protein purification operations are desirable but not essential for this role.
- The successful person will have previous experience of working in a third level training and or educational environment.
APPLICATION PROCESS
To apply for this position please forward your CV and cover letter to careers@nibrt.ie
Please include your name and the position which you are applying for in the subject line. Please note that the successful candidate may be required to supply parchments of degrees/qualifications/work permits. Informal enquiries can be made in confidence by contacting our Project Manager, Therese Keohane at careers@nibrt.ie
VACANCY SUMMARY
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POSITION AVAILABLE |
Bioprocessing Trainer (multiple vacancies) |
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LOCATION |
Dublin, Ireland |
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DEPARTMENT |
Training Department |
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HIRING MANAGER |
John Milne, Training Director |
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CONTRACT TYPE |
Permanent Full-time position |
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SALARY & BENEFITS |
Competitive salary and excellent suite of benefits. Benefits include: pension, private health insurance, income protection scheme, 25 days annual leave plus up to 3 additional company days off, generous training and career development supports, flexible working hours and work from home set up supported |
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APPLICATION DATE |
Open for applications |
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INTERVIEW DATES |
As soon as available (position to be filled as soon as possible) |
ORGANISATION OVERVIEW
The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin that provides training and research solutions to the global biopharmaceutical manufacturing sector. NIBRT arose from an innovative collaboration between University College Dublin, Trinity College Dublin, Dublin City University and the Institute of Technology, Sligo, with core funding by the Government of Ireland through Ireland’s inward investment agency, IDA Ireland. NIBRT’s 6,500 M² facility has 90+ employees currently and houses fully operational pilot plants for biologics manufacturing training to industry and education as well as multiple research laboratories focussed on biopharmaceuticals manufacturing research.
WORKING IN NIBRT
Our dynamic and highly skilled training team strives for excellence in all that it does and achieves this through a culture of mutual support, collaborative learning, and dedication. Specific opportunities for professional growth include:
- Unrivalled and broad-ranging experience in all aspects of the production, analysis, and regulation of the most advanced therapies on the market.
- Upskilling through attendance of international conferences, training courses and further education.
- Development of valuable transferrable skills such as oral and written communication, public speaking, project management and customer service.
Employees also enjoy additional benefits such as generous annual leave, flexi time and home working arrangements, support for further education, permanent health insurance and pension benefits.
ROLE PURPOSE
The purpose of this role is to develop and deliver training content to a wide variety of clients in the bioprocessing sector. The successful candidate will participate as a member of the NIBRT Training Team and will support the Training Director and Training Manager across all relevant areas.
DUTIES WILL INCLUDE:
- Development and delivery of training material including lectures and practical content in biopharmaceutical processing operations.
- Day to day operation of pilot plant facilities and laboratory equipment in NIBRT’s pilot production training facility.
- Implementation and maintenance of documentation for the NIBRT facility and business activities (SOPs, production batch records, project proposals and technical reports).
- Design, and delivery of customised training materials for clients onsite, online or offsite.
- Measurement of training effectiveness using a variety of assessment tools.
- Self-directed learning to ensure current knowledge of bioprocessing and an awareness of industry trends and advances.
- Ensuring safe operation and maintenance of laboratory and plant equipment and liaising with facilities team at NIBRT to resolve problems.
- Supporting NIBRT in the design and delivery of new and expanded methods of training (e.g. eLearning, blended learning etc.)
- Hosting tours of NIBRT pilot production plant and attend business development meetings with prospective clients.
- Represent the training department at company events (which may on occasion be during evenings or weekends).
- Any other reasonable duties as may be required from time to time by your manager.
YOUR PROFILE:
- You will hold a PhD in related scientific field (Life Science/Biopharmaceutical Processing/Engineering) OR a BSc/MSc in a related scientific field combined with relevant (bio) pharmaceutical industry experience.
- Detailed practical knowledge of bioprocessing manufacturing operations is essential.
- Documented interest, knowledge, or experience in one or more of the following is desired:
- Cell and gene therapies
- Vaccine manufacture
- QC Microbiology
- Sterile Fill Finish & aseptic processing of final drug product
- Biopharma 4.0 technologies
- Automation for Biopharma (DeltaV, LIMS etc.)
- QC Bioanalytics
- Drug Substance Manufacture
(Cover letter should clearly state which area applicant has knowledge/experience in)
- Motivated self-starter, capable of working under their own initiative as part of a busy and dynamic training team.
- Excellent interpersonal and verbal and written communication skills are essential for this role.
APPLICATION PROCESS
- To apply for this position please forward your CV, cover letter and the names and contact details of two referees in a combined PDF document to NIBRT at careers@nibrt.ie, we are seeking to fill positions as soon as possible. Please include your name and ‘Bioprocessing Trainer vacancy’ in the subject line. (The successful candidate may be required to supply evidence of degrees/qualifications/work permits). Informal enquiries can be made by contacting our HR team at careers@nibrt.ie
- Please note we are seeking a number of new trainers for the team!
#A
NIBRT does not accept unsolicited resumes from agencies and/or search firms for any job posted on this or a referring site. Without a valid signed search agreement in place for the position listed, NIBRT will not pay a fee to the agency or search firm in the event that a candidate is hired for a position as a result of an unsolicited agency or search firm referral.
NIBRT Employee Benefits
35 Hour Week
35 hours per week, Monday to Friday
Annual Leave
25 days per year, plus up to 3 company days
Pension
Defined contribution (5%) pension scheme
Health Insurance
NIBRT pay your health insurance plan
Life Insurance
Death in Service Life Assurance cover
Education
Education assistance, paid study time
Flexitime
Flexi start & finish times outside of core hours
Work From Home
Excellent work remotely supports inc. office fit out
Tax Savers
Travel Saver Tickets / Bike to work scheme
EAP
Extensive LAYA Employee Assistance Scheme
Our Values at NIBRT
Collaboration
Innovation
Respect
Client Focus
Learning Organisation
Excellence
Safety
A Day In The Life of a NIBRT Employee
Stephen McCann
What is a typical day in the life like for a NIBRT team member?
As a technician in NIBRT, my day-to-day activities are varied and engaging. No day is the same in NIBRT. There is always work to be found with many projects available to dip into.
The work covers all areas of the biopharmaceutical industry. In one day, I can set-up a stainless-steel bioreactor, run a clean-in-place cycle on a chromatography column, and troubleshoot problems with a restricted access barrier system. This is not to mention preparing reagents for the operation of analytical equipment like a spectrophotometer or UPLC machine.
The range of equipment I operate and maintain covers a large range. In the area of upstream alone, I have worked on old autoclavable bioreactors to more state-of-the-art wave bag bioreactors for cell and gene therapy. New pieces of equipment are bought regularly and afford me a great opportunity to engage with equipment at different levels. We have recently got a new in-line dilution skid which I have performed an SAT on, along with the development of its operating parameters and its use.
This work allows me to challenge myself on a day-to-day basis alongside working with a team that is always striving for better. Your voice matters in the training team in NIBRT, with a large degree of autonomy granted for you to get your work done in a manner that best befits the team and its goals. This has led to me being very happy in my current role and looking forward to what the future has to offer for NIBRT.
Adam Bergin
What is a typical day in the life like for a NIBRT team member?
There is never a “typical” work day in my role as a PhD student. This is what I like most about what I do; I am always trying to think of unique experiments as part of my research. I have been in NIBRT for three years, and I can honestly say that my experience so far have been a pleasure. My colleagues in the CTG lab are always supportive of my goals and advise me on the best course of action. I enjoy a balance of conducting wet lab work in NIBRT, but also availing of the facilities that are available to me as a UCD student. Everything I need is at my doorstep.
My project requires me to perform bench scale cell culture work, with the ultimate goal of monitoring cell viability in bioreactors using novel analytical technologies. I have access to modern and well-maintained equipment that allows my research to flourish. The research team in NIBRT is a tight-knit group, which is particularly useful during my PhD studies as I have access to a wealth of knowledge and experience. There are frequent seminars and spotlight sessions within NIBRT to keep us up to date on our newest findings.
Ultimately the experiments I perform allow me the opportunity to speak at conferences and publish articles. So far during my time in NIBRT, I have travelled to the United States and Denmark to speak at globally recognizes society meetings. Now that my four years are coming to a close, I look forward to concluding my lab work and submitting my final thesis. I would recommend NIBRT wholeheartedly to anybody who has the opportunity to join our team.
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NIBRT has received the "HR Excellence in Research" designation, identifying NIBRT as a provider of a high standard working environment for researchers. This award recognises NIBRT’s equitable recruitment and appraisal procedures and its commitment to implement the principles of 40 Principles of Charter and Code 2005 Conduct for the Recruitment of Researchers (the Charter and Code). Read more
NIBRT is delighted to have been awarded Investors in Diversity Bronze accreditation from the Irish Centre for Diversity in recognition of our commitment to a diverse and equal workplace. Investors in Diversity Bronze affirms that the organisation has built a strong foundation to embed Diversity & Inclusion across the operation and is equipped for the journey of becoming more equitable and inclusive.
