Course Descriptor
This course provides an introduction to the typical upstream operations carried out in a biopharmaceutical manufacturing facility. This course will include both hands-on practical and theory components covering cell vial thaw, aseptic techniques, cell counting, metabolic analysis, scale up, and bioreactor operation. Equipment such as single-use rocking bioreactors stirred-tank reactors, as well as stainless steel reactors, will all be utilised to reflect the current state of biopharmaceutical manufacturing technology.
This course is designed for operators, technical staff, engineers and managers wishing to increase their knowledge of the upstream operations in a modern bioprocessing plant.
Course Delivery Method: Blended online and onsite training
- Two mornings online theory
- Two days NIBRT practicals
Course Costs:
- Two mornings online theory only: €950
- Full course of Two mornings online theory and Two days NIBRT Practicals €2850
| February Delivery Online Theory – 20th & 21st Full course – 20th & 21st (online theory) + 27th & 28th (onsite practicals) |
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June Delivery |
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September Delivery |
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November/December Delivery Full course – 27th & 28th November (online theory) + 04th & 05th December (onsite practicals) |
Introduction to Upstream Processing Operations
€950.00 – €2,850.00
Dates:
- Course 1 06/06/2023 - 07/06/2023
Online Theory – 06th & 07th June 2023
€950.002 Places Remaining
- Course 2 06/06/2023 - 14/06/2023
Full course – 06th & 07th June 2023 (online theory) + 13th & 14th June 2023 (onsite practicals)
€2,850.00Out of stock
- Course 3 05/09/2023 - 06/09/2023
Online Theory – 05th & 06th September 2023
€950.003 Places Remaining
- Course 4 05/09/2023 - 13/09/2023
Full course – 05th & 06th September 2023 (online theory) + 12th & 13th September 2023 (onsite practicals)
€2,850.00Out of stock
- Course 5 27/11/2023 - 28/11/2023
Online Theory – 27th & 28th November 2023
€950.002 Places Remaining
- Course 6 27/11/2023 - 05/12/2023
Full course – 27th & 28th November 2023 (online theory) + 04th & 05th December 2023 (onsite practicals)
€2,850.00Out of stock
Suitable for:
This course is designed for operators, technical staff, engineers and managers wishing to increase their knowledge of the upstream operations in a modern bioprocessing plant.
Who should attend
This course is designed for operators, technical staff, engineers and managers wishing to increase their knowledge of the upstream operations in a modern bioprocessing plant.
Key topics covered
- Overview of the biopharmaceutical production process
- Mammalian cell culture aseptic technique
- Analysis of cell growth and nutrients in culture
- Cell culture scale up equipment including shake flasks and disposable bioreactors
- Preparation of a 150L stainless steel bioreactor for steam in place (SIP)
- Set up and operation of a 30L stainless steel seed bioreactor including inoculation and sampling.
Learning outcomes
Upon successful completion of this module the learner will be able to:
- Describe the practice of culturing mammalian cells in an aseptic environment from small to large scale
- List the equipment required for scale up of mammalian cultures
- Describe how the process of inoculating a stainless steel seed bioreactor is carried out.
- Use GDocP to follow and complete SOPs, batch records and log books.
- Count cells using both an automated and manual method
- Interpret the nutrient and metabolite levels of cell culture medium
- Prepare and run an SIP procedure on a 150L stainless steel bioreactor
Assessment
A competency based assessment will be undertaken at the end of the course. This will certify proficiency in the theory and practical skills.
