Vacancy Summary
The National Institute for Bioprocessing Research and Training (‘NIBRT’) is a global centre of excellence, headquartered in Dublin that provides training and research solutions to the global biopharmaceutical manufacturing sector.
NIBRT arose from an innovative collaboration between University College Dublin, Trinity College Dublin, Dublin City University and the Institute of Technology, Sligo, with core funding by the Government of Ireland through Ireland’s inward investment agency, IDA Ireland.
NIBRT’s 6,500 M² facility has 90+ employees currently and houses fully operational pilot plants for biologics manufacturing training to industry and education as well as multiple research laboratories focussed on biopharmaceuticals manufacturing research.
Position Available
Cell and Gene Therapy Scientist
Location
NIBRT, Dublin
Department
ATMP (CONCEPT)
Hiring Manager
Clair Gallagher
Contract Type
36 months, Fixed Term Contract
Application Date
Open for applications
Interview Dates
As soon as available (position to be filled as soon as possible)
Salary & Benefits
Competitive salary and excellent suite of benefits including pension, private health insurance, income protection scheme, 25 days annual leave plus up to 3 additional company days off, generous training and career development supports, flexible working hours and work from home set up supported.
Role Purpose
We are currently searching for a dynamic, hard-working laboratory-based Scientist to join our team at CONCEPT. CONCEPT is a brand-new, state-of-the-art facility constructed at NIBRT, with access to emerging technology platforms. We aim to provide a National Core Facility for researchers and the biopharmaceutical industry to access and drive rapid generation of optimised cell lines for production of recombinant proteins, mABs, cell therapies, gene therapies and RNA therapeutics.
This position offers a unique opportunity to develop expertise and experience in Advance Therapeutic Medicinal Product development. This dynamic and exciting area of research has rapidly expanded in recent years, offering novel and real-world treatment options for patients suffering from recalcitrant and life-limiting conditions.
Key Responsibilities
The key responsibilities of the job include:
- Attending scheduled training and developing expertise in relevant instrumentation and techniques.
- Assisting in experimental design.
- Developing and validating methods and Standard Operating Procedures.
- Performing experiments with high precision, reproducibility, quality control and validation.
- Generating and completing records, with precision and accuracy in a timely manner.
- Reporting progress, experimental issues and bottlenecks to facilitate continued process and operational improvement.
- Generating and presenting data, publication-ready plots and reports that accurately represent experimental data to stakeholders.
Essential Criteria
- A PhD or MSc in immunology, cell biology, molecular biology or another relevant field is essential.
- Excellent cell culture skills, including stem cell and immune cell culture experience.
- Experience processing blood cells and separating subpopulations.
- Demonstrated expertise in the genetic manipulation of primary human T cells using gene editing tools.
- Hands-on experience in developing and characterizing CAR-T, other Cell Therapies or Gene Therapies.
- Experience performing tumour immunology assays which interrogate T cell function in vitro (e.g. cellular activation, cytokine release, proliferation, and killing).
- Experience in RT-PCR and Sanger sequencing.
- Experience in cloning and vector design work.
Desirable Criteria
- Additional experience within the field of biopharmaceuticals, biotechnology or biomedical science is desired.
Required Skills & Competencies
- A passion for laboratory-based research, method development and a desire to trouble-shoot and optimise experiments to produce high quality outputs.
- A passion for detailed record keeping and schedule adherence.
- A proven ability to work well independently and as part of a team.
How To Apply?
To apply for this position please forward your CV and cover letter to careers@nibrt.ie
Please include your name and the position which you are applying for in the subject line. Please note that the successful candidate may be required to supply parchments of degrees/qualifications/work permits.
Informal enquiries can be made in confidence by contacting our Project Manager, Therese Keohane at careers@nibrt.ie
NIBRT is an Equal Opportunities Employer.
Awards and Recognition
